Six & Twenty Distillery

About Six & Twenty Distillery

Nestled in the heart of Greenville, South Carolina, Six & Twenty Distillery is where tradition meets innovation. At 556 Perry Ave, this craft distillery invites you to explore a world of finely crafted spirits that pay homage to local heritage and sustainability. Known for its small-batch whiskies, vodkas, and unique blends, Six & Twenty utilizes locally sourced ingredients to create flavors that are as bold as they are refined. Step into our inviting space where you can enjoy tastings, tours, and the warm Southern hospitality that defines us. Whether you're a connoisseur or a curious newbie, Six & Twenty promises an authentic experience, bridging the past and present with every sip. Join us in raising a glass to craftsmanship, community, and creativity. Discover your new favorite spirit at Six & Twenty—where every bottle tells a story.